Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38655920 | 1.00 | MAOB (0.65) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL1549058 | 0.86 | KCNH2 (0.55) | MAOBLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21340831 | 0.85 | MAOB (0.65) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL12443168 | 0.85 | PTPN1 (0.53) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL12423201 | 0.85 | MAOB (0.69) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL15474227 | 0.85 | MAOB (0.52) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL17644774 | 0.84 | MAOB (0.68) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL14018700 | 0.84 | MAOB (0.54) | MAOBPARP15PARP10PARP14TDP1 | |
| SCHEMBL3625841 | 0.83 | MAOB (0.67) | MAOBPARP15PARP10PARP14TDP1 | |
| Hydrochloric Acid SCHEMBL28551904 | 0.82 | MAOB (0.69) | MAOBPARP15PARP10PARP14TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819303-A1 | GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE | Shanghai Hutchison Pharmaceuticals Limited (CN) | 2021-05-12 | — | — | EP | disclosed |
| WO-2020210485-A1 | PROCESS FOR PREPARING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES | BIOGEN MA INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| EP-2598482-B1 | ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE | ORYZON GENOMICS SA (ES) | 2018-04-04 | — | — | EP | disclosed |
| US-9187437-B2 | Substituted oxadiazole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-11-17 | — | — | US | disclosed |
| US-20130190361-A1 | SUBSTITUTED OXADIAZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-25 | — | — | US | disclosed |
| US-20100130583-A1 | PROLINAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS | GLAXO GROUP LIMITED (GB) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190361-A1 | SUBSTITUTED OXADIAZOLE COMPOUNDS | S1PR1, S1PR3, S1PR2 | MAOB 1630/4885PARP15 1137/4885PARP10 1599/4885 |
| US-20100130583-A1 | PROLINAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS | SCN1A, SCN3A, SCN2A | MAOB 3647/4885PARP15 1604/4885PARP10 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.