Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 9/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 3/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877502 | 0.86 | PARP10 (0.58) | PTPN1MAOBPARP15PARP10PTPN2 | |
| SCHEMBL13320309 | 0.85 | MAOB (0.65) | MAOBPARP15PARP10PARP14LMNA | |
| SCHEMBL38655920 | 0.85 | MAOB (0.65) | MAOBPARP15PARP10PARP14LMNA | |
| SCHEMBL21084234 | 0.84 | LMNA (0.57) | MAOBPARP15PARP10PARP14LMNA | |
| SCHEMBL7239415 | 0.83 | MAOB (0.58) | PTPN1MAOBPARP15PARP10PTPN2 | |
| SCHEMBL21083437 | 0.81 | MAOB (0.55) | PTPN1MAOBPARP15PARP10PARP14 | |
| SCHEMBL15474227 | 0.81 | MAOB (0.52) | MAOBPARP15PARP10PARP14LMNA | |
| SCHEMBL14018700 | 0.80 | MAOB (0.54) | MAOBPARP15PARP10PARP14LMNA | |
| SCHEMBL8877320 | 0.79 | PTPN1 (0.64) | PTPN1MAOBPARP15PARP10PTPN2 | |
| SCHEMBL8876594 | 0.79 | PTPN1 (0.60) | PTPN1MAOBPARP15PARP10PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098801-A1 | INFLAMMATORY DISEASE TREATMENT | PULMAGEN THERAPEUTICS (INFLAMMATION) LIMITED (GB) | 2011-08-18 | — | — | WO | disclosed |