SCHEMBL3625841

SCHEMBL3625841

Oc1ccc(OCc2ccccc2F)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.67
PARP15 Q460N3 2/20 0.66
PARP10 Q53GL7 2/20 0.66
PARP14 Q460N5 1/20 0.66
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
CASP3 P42574 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
PKM P14618 2/20 0.56
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
ESR1 P03372 1/20 0.56
TP53 P04637 1/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
ALOX12 P18054 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12423201 0.86 MAOB (0.69) MAOBPARP15PARP10PARP14NPC1
SCHEMBL17644774 0.86 MAOB (0.68) MAOBPARP15PARP10PARP14NPC1
SCHEMBL10897051 0.86 LMNA (0.65) MAOBPARP15PARP10PARP14KDM4E
SCHEMBL7025478 0.85 MAOB (0.54) MAOBPARP15PARP10PARP14NPC1
SCHEMBL15079383 0.85 MAOB (0.51) MAOBPARP15PARP10PARP14NPC1
SCHEMBL7239415 0.84 MAOB (0.58) MAOBPARP15PARP10PARP14NPC1
Hydrochloric Acid SCHEMBL28551904 0.84 MAOB (0.69) MAOBPARP15PARP10PARP14NPC1
SCHEMBL2937570 0.84 MAOB (0.71) MAOBPARP15PARP10PARP14NPC1
SCHEMBL2950518 0.83 MAOB (0.71) MAOBPARP15PARP10PARP14NPC1
SCHEMBL311630 0.83 MAOB (0.65) MAOBPARP15PARP10PARP14NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116265458-A Benzothiophene derivative, preparation method and application thereof 中国科学院上海药物研究所 2023-06-20 CN disclosed
WO-2019170088-A1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 北京赛特明强医药科技有限公司 2019-09-12 WO disclosed
EP-2036878-B1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-22 EP disclosed
US-7745669-B2 Process for production of alcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-29 US disclosed
US-20090259074-A1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-15 US disclosed
EP-2036878-A1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2009-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090259074-A1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND XDH, ADH5, ADH1A MAOB 499/4885PARP15 2809/4885PARP10 1285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.