Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355967 | 1.00 | CASP3 (0.57) | CASP3KMT2ACTSBMDM4TP53 | |
| SCHEMBL3039215 | 1.00 | CASP3 (0.57) | CASP3KMT2ACTSBMDM4TP53 | |
| SCHEMBL29664082 | 1.00 | CASP3 (0.57) | CASP3KMT2ACTSBMDM4TP53 | |
| SCHEMBL29426432 | 0.89 | CASP3 (0.49) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL24785654 | 0.88 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL30291780 | 0.88 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL24785651 | 0.88 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL13323300 | 0.87 | CASP3 (0.49) | CASP3KMT2ACTSBMDM4TP53 | |
| SCHEMBL4552562 | 0.86 | CASP3 (0.71) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL31498750 | 0.86 | CASP3 (0.71) | CASP3KMT2AMDM4TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709484-B1 | Substituted melanocortin receptor-specific piperazine compounds | PALATIN TECHNOLOGIES, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709484-B1 | Substituted melanocortin receptor-specific piperazine compounds | PALATIN TECHNOLOGIES, INC. (US) | 2010-05-04 | — | — | US | disclosed |