Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291780 | 1.00 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL24785651 | 1.00 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL29664082 | 0.88 | CASP3 (0.57) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL8355967 | 0.88 | CASP3 (0.57) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL3039215 | 0.88 | CASP3 (0.57) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL13323320 | 0.88 | CASP3 (0.57) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL119546 | 0.84 | MDM4 (0.54) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL3728714 | 0.84 | MDM4 (0.54) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL29816502 | 0.84 | MDM4 (0.54) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL3730261 | 0.84 | MDM4 (0.54) | CASP3MDM4TP53HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265577-A2 | CORONAVIRUS ENZYME MODULATORS, METHODS OF SYNTHESIS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-12-22 | — | — | WO | disclosed |