Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.48 |
| ▸ | ASPH | Q12797 | 5/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 3/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14818769 | 0.80 | PDE3B (0.43) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL4220452 | 0.80 | KDM4E (0.41) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL1002512 | 0.80 | KDM4E (0.52) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL19857460 | 0.80 | KDM4E (0.62) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL3798200 | 0.78 | KDM4E (0.46) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL2238874 | 0.78 | DPP4 (0.47) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL14284234 | 0.78 | KDM4E (0.46) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL3112069 | 0.78 | KDM4E (0.50) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL4443123 | 0.78 | KDM4E (0.46) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL31500594 | 0.78 | DPP4 (0.47) | KDM4EASPHKDM8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| EP-1489174-B1 | METHOD OF MODIFYING PROTEIN PROPERTIES | NAT INST OF TECHNOLOGY AND EVALUATION (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-20130316401-A1 | Method for Modifying a Property of a Protein | AJINOMOTO CO., INC. (JP) | 2013-11-28 | — | — | US | disclosed |
| US-8510053-B2 | Method for modifying a property of a protein | AJINOMOTO CO., INC. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-7560565-B2 | Method for preparing derivatives of 3-hydroxypicolinic acid | BAYER CROPSCIENCE SA (FR) | 2009-07-14 | — | — | US | disclosed |
| US-20080176266-A1 | Biomarkers Of Metabolic Responses To Hepatotoxicants And Carcinogens | METABOLON, INC. | 2008-07-24 | — | — | US | disclosed |
| US-20060040995-A1 | Method for preparing hydroxypicolinic scid derivatives | AVENTIS CROPSCIENCE, S.A. (FR) | 2006-02-23 | — | — | US | disclosed |
| US-20050233308-A1 | Method for modifying a property of a protein | AJINOMOTO CO., INC. (JP) | 2005-10-20 | — | — | US | disclosed |
| EP-1489174-A1 | METHOD OF MODIFYING PROTEIN PROPERTIES | National Institute of Technology and Evaluation (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040995-A1 | Method for preparing hydroxypicolinic scid derivatives | CYP2F1, CYP21A2, CYP26B1 | KDM4E 3035/4885ASPH 509/4885KDM8 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.