Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ASPH | Q12797 | 3/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
| ▸ | GABRD | O14764 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349928 | 0.82 | KDM4E (0.44) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL22688920 | 0.81 | KDM4E (0.47) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL1243693 | 0.79 | KDM4E (0.50) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL29860445 | 0.79 | KDM4E (0.50) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL1332334 | 0.78 | KDM4E (0.48) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL1336311 | 0.78 | KDM4E (0.44) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL30781521 | 0.78 | KDM4E (0.44) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL3716415 | 0.77 | MAP4K1 (0.39) | KDM4EALDH1A1CYP3A4KDM5AEGLN1 | |
| SCHEMBL19857460 | 0.77 | KDM4E (0.62) | KDM4EASPHKDM8MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL20239059 | 0.76 | KDM4E (0.61) | KDM4EASPHKDM8MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133907-A1 | HEXADENTATE CHELATORS IN INFLAMMATORY BOWEL DISEASE | GHISALBERTI CARLO (BR) | 2010-11-25 | — | — | WO | disclosed |