Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15321258 | 0.85 | EGFR (0.38) | EGFR | |
| Hydrochloric Acid SCHEMBL15321017 | 0.84 | EGFR (0.37) | EGFR | |
| SCHEMBL16004612 | 0.83 | EGFR (0.37) | EGFR | |
| SCHEMBL3964364 | 0.79 | EGFR (0.47) | EGFRTP53L3MBTL1PPARGPPARD | |
| SCHEMBL2605809 | 0.79 | EGFR (0.47) | EGFRTP53L3MBTL1PPARGPPARD | |
| SCHEMBL3958089 | 0.79 | EGFR (0.47) | EGFRTP53L3MBTL1PPARGPPARD | |
| SCHEMBL261041 | 0.79 | CHRNB2 (0.40) | CHRNB2CHRNA4L3MBTL1 | |
| Citric Acid SCHEMBL15321217 | 0.76 | ALDH1A1 (0.35) | EGFR | |
| Citric Acid SCHEMBL15321213 | 0.76 | ALDH1A1 (0.35) | EGFR | |
| SCHEMBL15321059 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158842-A1 | NATURAL SKIN WHITENER: 4-HYDROXY-OXINDOLE-3-ACETIC ACID | SPECTRUM DYNAMICS LLC | 2010-06-24 | — | — | US | disclosed |