Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.42 |
| ▸ | TDO2 | P48775 | 7/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325757 | 0.80 | IDO1 (0.39) | IDO1TDO2DHODHMAPTALDH1A1 | |
| SCHEMBL9908306 | 0.80 | DHODH (0.39) | IDO1TDO2DHODHALDH1A1HSD17B10 | |
| SCHEMBL13325724 | 0.79 | NPC1 (0.41) | IDO1TDO2DHODHMAPTCYP2C9 | |
| SCHEMBL13325639 | 0.78 | IDO1 (0.48) | IDO1TDO2DHODHMAPTCYP2C9 | |
| SCHEMBL13325987 | 0.76 | IDO1 (0.39) | IDO1TDO2DHODHALDH1A1HSD11B1 | |
| SCHEMBL13325762 | 0.74 | FGFR1 (0.40) | IDO1TDO2DHODHMAPTALDH1A1 | |
| SCHEMBL2967466 | 0.74 | IDO1 (0.54) | IDO1TDO2DHODHSMN1; SMN2 | |
| SCHEMBL5960134 | 0.71 | IDO1 (0.54) | IDO1TDO2DHODHMAPTALDH1A1 | |
| SCHEMBL29042740 | 0.67 | MPO (0.49) | IDO1TDO2MAPTCYP2C9CYP2C19 | |
| SCHEMBL15413314 | 0.66 | ALDH1A1 (0.52) | MAPTCYP2C9CYP2C19ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709655-B2 | Clickphosphines for transition metal-catalyzed reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | WEE1, WEE2, ITK | IDO1 2304/4885TDO2 2237/4885DHODH 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.