Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | BCL6 | P41182 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.49 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829781 | 0.92 | RAB9A (0.65) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL14293830 | 0.91 | RAB9A (0.67) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL4838260 | 0.90 | RAB9A (0.62) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL4836573 | 0.88 | BCL6 (0.68) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL14533521 | 0.87 | RAB9A (0.58) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL13325997 | 0.87 | RAB9A (0.60) | RAB9ACTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL4829545 | 0.85 | MAPT (0.60) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL13326006 | 0.84 | RAB9A (0.74) | RAB9ACTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL14268318 | 0.84 | BCL6 (0.63) | RAB9ABCL6CTSLCTSSCTSK | |
| SCHEMBL4835764 | 0.84 | MAPT (0.69) | RAB9ABCL6CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |