Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326019 | 0.87 | RAB9A (0.66) | RAB9APDE4ACTSLCTSSCTSK | |
| SCHEMBL13326054 | 0.83 | ALDH1A1 (0.57) | RAB9AFLT3PDE4ACTSSCTSK | |
| SCHEMBL4829781 | 0.83 | RAB9A (0.65) | RAB9APDE4ACTSLCTSSCTSK | |
| SCHEMBL14293830 | 0.82 | RAB9A (0.67) | RAB9APDE4ACTSLCTSSCTSK | |
| SCHEMBL4838260 | 0.81 | RAB9A (0.62) | RAB9APDE4ACTSLCTSSCTSK | |
| SCHEMBL13325996 | 0.81 | PTK2 (0.62) | FLT3PTK2MEN1MAPTKMT2A | |
| SCHEMBL3287809 | 0.80 | CTSL (0.54) | FLT3PTK2CTSLCTSSCTSK | |
| SCHEMBL13326006 | 0.80 | RAB9A (0.74) | RAB9APDE4ACTSLCTSSCTSK | |
| SCHEMBL4836573 | 0.79 | BCL6 (0.68) | RAB9ACTSLCTSSCTSKCCR4 | |
| SCHEMBL14533521 | 0.79 | RAB9A (0.58) | RAB9APDE4ACTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |