Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | BCHE | P06276 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | BACE1 | P56817 | 4/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594243 | 0.87 | BCHE (0.48) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL13327267 | 0.81 | ACHE (0.59) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL3047685 | 0.81 | ACHE (0.62) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL15001013 | 0.78 | ACHE (0.62) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL6159635 | 0.75 | MAPK1 (1.00) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL4046485 | 0.75 | MAPK1 (0.56) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL6747487 | 0.74 | ACHE (0.54) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11102389 | 0.74 | MAPK1 (0.97) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL2840739 | 0.74 | ACHE (0.70) | MAPK1BCHEACHEBACE1SIGMAR1 | |
| SCHEMBL11099318 | 0.73 | MAPK1 (0.54) | MAPK1BCHEACHEBACE1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |