Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.62 |
| ▸ | BACE1 | P56817 | 7/20 | 0.62 |
| ▸ | BCHE | P06276 | 5/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122623 | 0.91 | BCHE (0.64) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL10656251 | 0.91 | BCHE (0.64) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL4591941 | 0.84 | SIGMAR1 (0.56) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL15001013 | 0.84 | ACHE (0.62) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL2840739 | 0.83 | ACHE (0.70) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL28055993 | 0.82 | ALDH1A1 (0.56) | ACHEBACE1BCHEKDM4E | |
| SCHEMBL28086924 | 0.82 | ALDH1A1 (0.56) | ACHEBACE1BCHEKDM4E | |
| SCHEMBL13327267 | 0.81 | ACHE (0.59) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL13327265 | 0.81 | MAPK1 (0.60) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL8408423 | 0.80 | ACHE (0.66) | ACHEBACE1BCHESIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484444-B | Synthesis method of N-benzyl-4-piperidine formaldehyde | 常州大学 | 2021-07-30 | — | — | CN | claimed |
| CN-111484444-A | Synthesis method of N-benzyl-4-piperidine formaldehyde | 常州大学 | 2020-08-04 | — | — | CN | claimed |
| US-5965579-A | ANTAGONISTS OF THE NEUROTENSIN RECEPTORS; INCREASING AFFINITY FOR HUMAN NEUROTENSIN RECEPTORS | SANOFI (FR) | 1999-10-12 | — | — | US | claimed |
| WO-1996032382-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1996-10-17 | — | — | WO | claimed |
| CN-111484444-B | Synthesis method of N-benzyl-4-piperidine formaldehyde | 常州大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-110776494-B | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2021-01-05 | — | — | CN | disclosed |
| EP-3753577-A1 | CHONDROCYTE PROLIFERATION PROMOTER, CHONDROCYTE PROLIFERATION PROMOTION METHOD, SCREENING METHOD FOR CHONDROCYTE PROLIFERATION PROMOTERS | Tokyo University of Science Foundation (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-111484444-A | Synthesis method of N-benzyl-4-piperidine formaldehyde | 常州大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-110776494-A | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-109415337-A | Piperidines as multiple endocrine neoplasia protein inhibitor | 密执安大学评议会 | 2019-03-01 | — | — | CN | disclosed |
| CN-101935316-B | Quinazoline compound and application thereof | JIANGSU SIMCERE PHARMACEUTICAL RESEARCH COMPANY LIMITED (CN) | 2014-10-22 | — | — | CN | disclosed |
| US-5939449-A | NOVEL COMPOUNDS HAVING HIGH AFFINITY FOR THE NEUROTENSIN RECEPTORS | SANOFI (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5936123-A | COMPOUNDS SUCH AS 3-ISOPROPYL-4-HYDRAZINOBENZOIC ACID AND ITS SALTS | SANOFI (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5925661-A | NERVOUS SYSTEM DISORDERS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |
| US-5723483-A | NEUROTENSIN ANTAGONIST, HYPOTENSIVE AGENTS AND FOR NEUROPSYCHIATRIC DISORDERS | SANOFI (FR) | 1998-03-03 | — | — | US | disclosed |
| WO-1996032382-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1996-10-17 | — | — | WO | disclosed |
| US-4409228-A | ANOREXIGENIC AGENTS | SANOFI (FR) | 1983-10-11 | — | — | US | disclosed |
| EP-0045980-B1 | COMPOUNDS USEFUL IN THE PREPARATION OF AMINOPIPERIDINES WITH ANORECTIC PROPERTIES | SANOFI S.A. (FR) | 1983-10-05 | — | — | EP | disclosed |
| EP-0021973-B1 | ANORECTIC AMINO PIPERIDINES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | SANOFI S.A. (FR) | 1982-12-08 | — | — | EP | disclosed |