Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.60 |
| ▸ | SHBG | P04278 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327487 | 1.00 | CYP19A1 (0.60) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL3338391 | 1.00 | CYP19A1 (0.60) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL7145526 | 1.00 | CYP19A1 (0.60) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL12153460 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL13327143 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL12153534 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL12153584 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL12858782 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL13327141 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR | |
| SCHEMBL13304378 | 0.82 | SMN1; SMN2 (0.63) | CYP19A1SHBGESR1SMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100151002-A1 | Guggulphospholipid Methods and Compositions | JINA PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151002-A1 | Guggulphospholipid Methods and Compositions | SGMS2, SGMS1, PLA2G5 | CYP19A1 406/4885SHBG 227/4885ESR1 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.