⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985823 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL2175496 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL132521 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL2177991 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL2173439 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL443449 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL2174526 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL2176899 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL536857 | 0.97 | LMNA (0.43) | — | |
| SCHEMBL1827462 | 0.97 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014878-B | Conjugated alkenyl zinc reagent, preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | claimed |
| CN-116535439-B | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2024-05-28 | — | — | CN | claimed |
| CN-116535439-A | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2023-08-04 | — | — | CN | claimed |
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | claimed |
| US-20230174581-A1 | PROCESSES AND AGENTS FOR GLAUCOMA | AUFBAU MEDICAL INNOVATIONS LIMITED (IE) | 2023-06-08 | — | — | US | claimed |
| CN-116003462-A | Silicon-based substituted chiral amine and preparation method and application thereof | 南开大学 | 2023-04-25 | — | — | CN | claimed |
| CN-115850328-A | Diphosphine ligand with cyclopropane skeleton and cobalt complex thereof, preparation method and application | 南开大学 | 2023-03-28 | — | — | CN | claimed |
| EP-4125994-A1 | PROCESSES AND AGENTS FOR GLAUCOMA | Aufbau Medical Innovations Limited (IE) | 2023-02-08 | — | — | EP | claimed |
| US-20220162219-A1 | Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof | UNIV JINAN (CN) | 2022-05-26 | — | — | US | claimed |
| CN-114249725-A | Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof | 南开大学 | 2022-03-29 | — | — | CN | claimed |
| EP-0920324-A2 | PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENTS AND A COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTIONS | PATHOGENESIS CORPORATION (US) | 1999-06-09 | — | — | EP | claimed |
| WO-1998020836-A9 | PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENTS AND A COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTIONS | — | 1998-10-08 | — | — | WO | claimed |
| US-5767068-A | BACTERICIDES | PATHOGENESIS CORPORATION (US) | 1998-06-16 | — | — | US | claimed |
| WO-1998020836-A2 | PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENTS AND A COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTIONS | PATHOGENESIS CORPORATION (US) | 1998-05-22 | — | — | WO | claimed |
| EP-0622372-B1 | New compound, leustroducsin H, its preparation and its therapeutic use | SANKYO CO (JP) | 1998-05-13 | — | — | EP | claimed |
| EP-0798304-A1 | REMEDIES FOR THROMBOCYTOPENIA | SUNTORY LIMITED (JP) | 1997-10-01 | — | — | EP | claimed |
| EP-0622372-A1 | New compound, leustroducsin H, its preparation and its therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-11-02 | — | — | EP | claimed |
| EP-0218688-B1 | DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS | THE UPJOHN COMPANY (US) | 1990-09-12 | — | — | EP | claimed |
| EP-0265127-A1 | Endotoxin assay | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-04-27 | — | — | EP | claimed |
| WO-1988002862-A1 | ENDOTOXIN ASSAY | HARVEY WILSON (GB) | 1988-04-21 | — | — | WO | claimed |