Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985823 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL2175496 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL2176899 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL2177991 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL2174526 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL132521 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL2173439 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL536857 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL443449 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 | |
| SCHEMBL294141 | 1.00 | LMNA (0.43) | LMNAKDM4CTRPV1KDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294275-B2 | Site-selective functionalization of glycopeptide antibiotics | YALE UNIVERSITY (US) | 2019-05-21 | — | — | US | claimed |
| US-20160039881-A1 | SITE-SELECTIVE FUNCTIONALIZATION OF GLYCOPEPTIDE ANTIBIOTICS | YALE UNIVERSITY (US) | 2016-02-11 | — | — | US | claimed |
| WO-2014160250-A9 | SITE-SELECTIVE FUNCTIONALIZATION OF GLYCOPEPTIDE ANTIBIOTICS | YALE UNIVERSITY (US) | 2015-12-17 | — | — | WO | claimed |
| WO-2014160250-A2 | SITE-SELECTIVE FUNCTIONALIZATION OF GLYCOPEPTIDE ANTIBIOTICS | YALE UNIVERSITY (US) | 2014-10-02 | — | — | WO | claimed |
| CN-101792474-B | Novel AzalomycinF microlide compounds and preparation method thereof and application thereof | INST TROPICAL BIOSCIENCE & BIOTECHNOLOGY CATAS | 2013-01-02 | — | — | CN | claimed |
| CN-101792474-A | Novel AzalomycinF microlide compounds and preparation method thereof and application thereof | INST TROPICAL BIOSCIENCE & BIOTECHNOLOGY CATAS | 2010-08-04 | — | — | CN | claimed |
| US-5936074-A | REACTING TEICOPLANIN WITH ECHINOCANDIN BETA DEACYLASE, THEN FORMING SALT AND/OR DEPROTECTING AMINO GROUP; BACTERICIDES AGAINST GRAM-POSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1999-08-10 | — | — | US | claimed |
| US-5869449-A | IMPROVED ANTIBACTERIAL ACTIVITY AGAINST SOME CLINICAL ISOLATES OF STAPHYLOCOCCI SOMEWHAT RESISTANT TO TEICOPLANIN. | GRUPPO LEPETIT S.P.A. (IT) | 1999-02-09 | — | — | US | claimed |
| EP-0873996-A1 | Process of deacylation of teicoplanin and product thereby obtained | ELI LILLY AND COMPANY (US) | 1998-10-28 | — | — | EP | claimed |
| WO-1998046580-A1 | DEACYLATION PROCESS AND PRODUCT | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | claimed |
| EP-0340245-B1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS | GRUPPO LEPETIT S.p.A. (IT) | 1992-08-19 | — | — | EP | claimed |
| WO-1992010516-A1 | 38-DECARBOXY-38-HYDROXYMETHYL DERIVATIVES OF TEICOPLANIN ANTIBIOTICS, AND A PROCESS FOR PREPARING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1992-06-25 | — | — | WO | claimed |
| EP-0465481-A1 | NEW SUBSTITUTED ALKYLAMIDE DERIVATIVES OF TEICOPLANIN. | LEPETIT SPA (IT) | 1992-01-15 | — | — | EP | claimed |
| EP-0460448-A2 | Use of C63-amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin against bacteria resistant to glycopeptide antibiotics | GRUPPO LEPETIT S.p.A. (IT) | 1991-12-11 | — | — | EP | claimed |
| WO-1990011300-A1 | NEW SUBSTITUTED ALKYLAMIDE DERIVATIVES OF TEICOPLANIN | GRUPPO LEPETIT S.P.A. (IT) | 1990-10-04 | — | — | WO | claimed |
| CN-1043941-A | 34-takes off the C63 amide derivatives of (N-acetyl glucosamine amido)-34-deoxidation-teicoplanins | LEPETIT SPA (IT) | 1990-07-18 | — | — | CN | claimed |
| EP-0376041-A2 | C63-Amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanins | GRUPPO LEPETIT S.p.A. (IT) | 1990-07-04 | — | — | EP | claimed |
| EP-0340245-A1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS. | LEPETIT SPA (IT) | 1989-11-08 | — | — | EP | claimed |
| CN-88101000-A | The alkylamide of the replacement of teicoplanin compounds | — | 1988-09-14 | — | — | CN | claimed |
| WO-1988006600-A1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS | GRUPPO LEPETIT S.P.A. (IT) | 1988-09-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039881-A1 | SITE-SELECTIVE FUNCTIONALIZATION OF GLYCOPEPTIDE ANTIBIOTICS | CUTA, VIP, GNE | LMNA 3000/4885KDM4C 4198/4885TRPV1 1147/4885 |
| US-10294275-B2 | Site-selective functionalization of glycopeptide antibiotics | CUTA, VIP, GNE | LMNA 3000/4885KDM4C 4198/4885TRPV1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.