Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | LGMN | Q99538 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 4/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19649074 | 0.98 | ACACB (0.35) | PHGDHWDR91P2RY12CYP17A1CYP21A2 | |
| SCHEMBL21005460 | 0.97 | PHGDH (0.33) | PHGDHWDR91P2RY12CYP17A1CYP21A2 | |
| SCHEMBL13327519 | 0.91 | PHGDH (0.35) | PHGDHWDR91P2RY12CYP17A1CYP21A2 | |
| SCHEMBL13327499 | 0.90 | ACACB (0.33) | PHGDHCYP17A1CYP21A2CYP11B1ACACB | |
| SCHEMBL13327506 | 0.89 | PHGDH (0.37) | PHGDHWDR91P2RY12RORC | |
| SCHEMBL19649072 | 0.88 | — | — | |
| SCHEMBL19903955 | 0.84 | ACHE (0.33) | PHGDHCYP17A1CYP21A2CYP11B1ACACB | |
| SCHEMBL18774380 | 0.82 | ACHE (0.31) | ACACBACHE | |
| SCHEMBL13327520 | 0.82 | ACHE (0.31) | PHGDHCYP17A1CYP21A2CYP11B1ACACB | |
| SCHEMBL13799669 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |
| US-7717964-B2 | Styryl thiol/disulfide compound with a hydroxy(cyclo)alkylamino unit, process for lightening keratin materials using same | L'OREAL S.A. (FR) | 2010-05-18 | — | — | US | disclosed |
| US-20090172897-A1 | STYRYL THIOL/DISULFIDE COMPOUND WITH A HYDROXY(CYCLO)ALKYLAMINO UNIT, PROCESS FOR LIGHTENING KERATIN MATERIALS USING SAME | L'OREAL S.A. (FR) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090172897-A1 | STYRYL THIOL/DISULFIDE COMPOUND WITH A HYDROXY(CYCLO)ALKYLAMINO UNIT, PROCESS FOR LIGHTENING KERATIN MATERIALS USING SAME | KRT18, TST, CYBA | PHGDH 1031/4885WDR91 3430/4885P2RY12 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.