SCHEMBL13328646

SCHEMBL13328646

CCCC1CCC(CCC2CCc3cc(OC)c(F)c(F)c3C2)CC1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
DRD2 P14416 5/20 0.33
DRD4 P21917 2/20 0.33
DRD3 P35462 2/20 0.33
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18088055 0.90 CHRM2 (0.34) CHRM2CHRM1CHRM3DRD2DRD3
SCHEMBL13328589 0.90 ACHE (0.33) ALDH1A1
SCHEMBL12018686 0.81 DRD2 (0.32) ALDH1A1CYP2D6CYP2C9ALOX15MAPK1
SCHEMBL15444516 0.79 CYP3A4 (0.32) CYP2D6CYP2C9MAPK1DRD2DRD3
SCHEMBL14494658 0.79 FYN (0.33) ALDH1A1CYP2C9MAPK1
SCHEMBL13360627 0.79 FYN (0.31)
SCHEMBL13328555 0.78 TLR4 (0.34)
SCHEMBL6402937 0.77 FYN (0.36) ALDH1A1
SCHEMBL14494571 0.76 TLR4 (0.32) CYP2C9
SCHEMBL18084735 0.76 HTR1D (0.37) ALDH1A1CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718232-B2 Nematic liquid crystal composition and liquid crystal display element that used the composition DAINIPPON INK & CHEMICAL, INC. (JP) 2010-05-18 US disclosed
US-7718232-B2 Nematic liquid crystal composition and liquid crystal display element that used the composition DAINIPPON INK & CHEMICAL, INC. (JP) 2010-05-18 US disclosed
EP-1591513-B1 NEMATIC LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE SAME DAINIPPON INK & CHEMICALS (JP) 2008-07-02 EP disclosed
US-20080149889-A1 Nematic Liquid Crystal Composition and Liquid Crystal Display Element That Used the Composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-06-26 US disclosed
US-20080149889-A1 Nematic Liquid Crystal Composition and Liquid Crystal Display Element That Used the Composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-06-26 US disclosed