Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943207 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11943304 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11943296 | 0.75 | MAPT (0.53) | ALDH1A1MAPTCYP2C19NPSR1POLB | |
| SCHEMBL11943284 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11946583 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11943286 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11943197 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11943203 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11954274 | 0.72 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL11946600 | 0.71 | LMNA (0.52) | ALDH1A1MAPTPOLBDCTPP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | ALDH1A1 2003/4885MAPT 3651/4885CYP3A4 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.