Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943155 | 0.90 | MAPT (0.52) | MAPTALDH1A1DCTPP1SMN1; SMN2KDM4E | |
| SCHEMBL11943257 | 0.84 | MAPT (0.48) | MAPTALDH1A1DCTPP1SMN1; SMN2KDM4E | |
| SCHEMBL13329125 | 0.79 | FAAH (0.48) | MAPTDCTPP1SMN1; SMN2KDM4EPKM | |
| SCHEMBL11943260 | 0.77 | KMT2A (0.50) | MAPTALDH1A1DCTPP1SMN1; SMN2MEN1 | |
| SCHEMBL11943270 | 0.77 | MAPT (0.48) | MAPTDCTPP1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL11943382 | 0.76 | MAPT (0.56) | MAPTALDH1A1DCTPP1SMN1; SMN2KDM4E | |
| SCHEMBL11943162 | 0.76 | SMN1; SMN2 (0.41) | MAPTALDH1A1DCTPP1SMN1; SMN2KDM4E | |
| SCHEMBL11943214 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1DCTPP1SMN1; SMN2KDM4E | |
| SCHEMBL16300919 | 0.74 | TRPV1 (0.51) | MAPTDCTPP1SMN1; SMN2KDM4ETRPV1 | |
| SCHEMBL11943153 | 0.73 | TRPV1 (0.50) | MAPTDCTPP1SMN1; SMN2TRPV1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | MAPT 3651/4885ALDH1A1 2003/4885DCTPP1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.