Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.74 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.70 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.67 |
| ▸ | SCD | O00767 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KLK7 | P49862 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483622 | 0.92 | MAP3K5 (0.77) | HSD17B1HSD17B2MAP3K5DYRK1ASCD | |
| SCHEMBL31024 | 0.92 | HSD17B1 (0.82) | HSD17B1HSD17B2MAP3K5DYRK1ASCD | |
| SCHEMBL13329390 | 0.91 | MAP3K5 (0.83) | MAP3K5DYRK1ASCDNPC1RAB9A | |
| SCHEMBL16554035 | 0.88 | HSD17B1 (0.76) | HSD17B1HSD17B2DYRK1ASCDNPC1 | |
| SCHEMBL16554101 | 0.87 | HTT (0.71) | HSD17B1HSD17B2DYRK1ASCDNPC1 | |
| SCHEMBL19464560 | 0.87 | HSD17B1 (0.74) | HSD17B1HSD17B2DYRK1ASCDNPC1 | |
| SCHEMBL12199347 | 0.87 | HSD17B1 (0.76) | HSD17B1HSD17B2DYRK1ASCDNPC1 | |
| SCHEMBL14807662 | 0.87 | MAP3K5 (0.70) | MAP3K5SCDNPC1RAB9AALDH1A1 | |
| SCHEMBL12199323 | 0.87 | HSD17B1 (0.76) | HSD17B1HSD17B2DYRK1ASCDNPC1 | |
| SCHEMBL12225869 | 0.87 | HSD17B1 (0.74) | HSD17B1HSD17B2MAP3K5DYRK1ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |