Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.76 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SCD | O00767 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.70 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199323 | 1.00 | HSD17B1 (0.76) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL31024 | 0.92 | HSD17B1 (0.82) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL16554035 | 0.88 | HSD17B1 (0.76) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL19464560 | 0.87 | HSD17B1 (0.74) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL13329360 | 0.87 | HSD17B1 (0.74) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL12225869 | 0.87 | HSD17B1 (0.74) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL29788 | 0.86 | HSD17B1 (0.82) | HSD17B1HSD17B2LRRK2NPC1RAB9A | |
| SCHEMBL13329184 | 0.86 | HSD17B1 (0.81) | HSD17B1HSD17B2LRRK2SCDHTT | |
| SCHEMBL12199320 | 0.86 | HSD17B1 (0.81) | HSD17B1HSD17B2LRRK2SCDHTT | |
| SCHEMBL31155 | 0.86 | HSD17B1 (1.00) | HSD17B1HSD17B2LRRK2SCDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110243846-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110243846-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | APP, APBA1, BACE1 | HSD17B1 3226/4885HSD17B2 3825/4885LRRK2 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.