Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304332 | 0.88 | DCTPP1 (0.42) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11953028 | 0.87 | ALDH1A1 (0.44) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11952504 | 0.78 | ALDH1A1 (0.46) | ALDH1A1DCTPP1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL11943112 | 0.74 | DCTPP1 (0.43) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11943111 | 0.71 | ALDH1A1 (0.48) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11943138 | 0.70 | ALDH1A1 (0.46) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11943132 | 0.70 | MAPT (0.46) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11943139 | 0.70 | KDM4E (0.46) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11953214 | 0.69 | ALDH1A1 (0.46) | ALDH1A1DCTPP1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11943158 | 0.68 | EPHX2 (0.46) | ALDH1A1DCTPP1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | ALDH1A1 2003/4885DCTPP1 209/4885RXFP1 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.