Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328925 | 0.86 | CNR1 (0.55) | CNR1CNR2HDAC6HDAC1MAOA | |
| SCHEMBL13360832 | 0.84 | KRAS (0.51) | CNR1CNR2HDAC6HDAC1 | |
| SCHEMBL2187186 | 0.77 | HDAC1 (0.57) | HDAC6HDAC1MAOAMAOBALDH1A1 | |
| SCHEMBL13328922 | 0.76 | HTR6 (0.48) | CNR1MAOAMAOB | |
| SCHEMBL13328924 | 0.76 | HTR6 (0.48) | HDAC6HDAC1MAOAMAOB | |
| SCHEMBL4139584 | 0.75 | ADRA2A (0.61) | HDAC6HDAC1KDM4EALDH1A1POLB | |
| SCHEMBL13329671 | 0.74 | HDAC6 (0.41) | CNR1CNR2HDAC6HDAC1MAOA | |
| SCHEMBL4134103 | 0.74 | HDAC6 (0.58) | HDAC6HDAC1KDM4EALDH1A1POLB | |
| SCHEMBL13329673 | 0.74 | CNR1 (0.40) | CNR1CNR2HDAC6HDAC1MAOA | |
| SCHEMBL13360755 | 0.72 | KRAS (0.53) | CNR1CNR2HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | CNR1, CNR2, OPRL1 | CNR1 1/4885CNR2 2/4885HDAC6 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.