Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19117072 | 0.89 | CYP19A1 (0.41) | ALDH1A1ADAM17CYP19A1GAASMN1; SMN2 | |
| SCHEMBL18256793 | 0.89 | CYP19A1 (0.41) | ALDH1A1ADAM17CYP19A1GAASMN1; SMN2 | |
| SCHEMBL22510548 | 0.85 | CYP19A1 (0.34) | ALDH1A1ADAM17CYP19A1PKM | |
| SCHEMBL18180516 | 0.83 | ADAM17 (0.42) | ALDH1A1ADAM17CYP19A1 | |
| SCHEMBL18929126 | 0.82 | MAPT (0.40) | ALDH1A1ADAM17CYP19A1 | |
| SCHEMBL19749316 | 0.81 | CYP19A1 (0.39) | ADAM17CYP19A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL12283587 | 0.79 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1CYP19A1APEX1BLM | |
| SCHEMBL16712848 | 0.79 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1CYP19A1APEX1BLM | |
| SCHEMBL18660819 | 0.79 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1CYP19A1APEX1BLM | |
| SCHEMBL25633537 | 0.79 | ADAM17 (0.36) | ALDH1A1ADAM17CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862023-A1 | CONJUGATES OF CELL-BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou DAC Biotech Co, Ltd (CN) | 2021-08-11 | — | — | EP | disclosed |
| US-20100159455-A1 | RECEPTOR FAMILY PROFILING | ENSEMBLE DISCOVERY | 2010-06-24 | — | — | US | disclosed |
| WO-2010017328-A2 | CYCLODEXTRIN CONJUGATES | RGO BIOSCIENCES LLC (US) | 2010-02-11 | — | — | WO | disclosed |