Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DNM2 | P50570 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329944 | 0.82 | DNM2 (0.47) | TRIM58DNM2KCNH3SLC29A1KMT2A | |
| SCHEMBL13329954 | 0.82 | DNM2 (0.66) | TRIM58TP53DNM2ALDH1A1SLC29A1 | |
| SCHEMBL13329992 | 0.79 | DNM2 (0.46) | TRIM58DNM2KCNH3SLC29A1KMT2A | |
| SCHEMBL13329958 | 0.78 | TP53 (0.69) | TRIM58TP53DNM2KCNH3ALDH1A1 | |
| SCHEMBL13329956 | 0.76 | TLR8 (0.65) | TP53DNM2KCNH3ALDH1A1NPC1 | |
| SCHEMBL13329955 | 0.76 | TLR8 (0.65) | TP53DNM2KCNH3ALDH1A1NPC1 | |
| SCHEMBL27873804 | 0.75 | TLR8 (0.62) | TP53KCNH3ALDH1A1NPC1MAPT | |
| SCHEMBL13329978 | 0.73 | TLR8 (0.52) | TRIM58TP53DNM2KCNH3ALDH1A1 | |
| SCHEMBL1733560 | 0.73 | KDM4E (0.53) | TRIM58KCNH3ALDH1A1NPC1MAPT | |
| SCHEMBL13329973 | 0.70 | TLR8 (0.57) | TP53DNM2KCNH3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |