Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 11/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329954 | 0.84 | DNM2 (0.66) | DNM2SLC29A1KMT2AHTTTRIM58 | |
| SCHEMBL13329944 | 0.82 | DNM2 (0.47) | DNM2SLC29A1KMT2AHTTTRIM58 | |
| SCHEMBL13329960 | 0.79 | TRIM58 (0.48) | DNM2SLC29A1KMT2ATRIM58KCNH3 | |
| SCHEMBL13329980 | 0.74 | DNM2 (0.56) | DNM2KMT2AHTTKCNH3 | |
| SCHEMBL17817154 | 0.73 | SLC29A1 (0.67) | DNM2SLC29A1KMT2AKCNH3 | |
| SCHEMBL13329996 | 0.71 | DNM2 (0.45) | DNM2KMT2AHTTKCNH3GBA1 | |
| SCHEMBL13329949 | 0.70 | DNM2 (0.74) | DNM2KMT2AHTTTRIM58KCNH3 | |
| SCHEMBL13329995 | 0.68 | DNM2 (0.52) | DNM2KMT2AHTTKCNH3 | |
| SCHEMBL13329942 | 0.68 | DNM2 (0.52) | DNM2SLC29A1KMT2ATRIM58KCNH3 | |
| SCHEMBL13329983 | 0.68 | HRH4 (0.43) | DNM2KMT2AHTTGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |