Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329974 | 0.83 | ESR1 (0.44) | HRH4HRH1TP53 | |
| SCHEMBL13309932 | 0.81 | HRH4 (0.60) | HRH4HRH1PTGDRTLR8 | |
| SCHEMBL9911093 | 0.80 | PTGDR (0.72) | PTGDR | |
| SCHEMBL17407827 | 0.79 | HRH4 (0.80) | HRH4HRH1TLR8 | |
| SCHEMBL3228726 | 0.79 | HRH4 (0.57) | HRH4HRH1PTGDRTLR8MEN1 | |
| SCHEMBL13329973 | 0.74 | TLR8 (0.57) | HRH4HRH1PTGDRTLR8TP53 | |
| SCHEMBL11309305 | 0.71 | MEN1 (0.56) | HRH4TP53MEN1KMT2A | |
| SCHEMBL5805069 | 0.71 | HRH4 (0.70) | HRH4HRH1TLR8 | |
| SCHEMBL28043771 | 0.71 | HRH4 (0.62) | HRH4HRH1PTGDRTLR8 | |
| SCHEMBL14869428 | 0.70 | CA1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |