Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450708 | 0.85 | ALDH1A1 (0.58) | HRH4HRH1MEN1ALDH1A1HPGD | |
| SCHEMBL13309932 | 0.85 | HRH4 (0.60) | HRH4HRH1ALDH1A1L3MBTL1PTGDR | |
| SCHEMBL8492272 | 0.83 | APP (0.54) | HRH4HRH1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL17407827 | 0.82 | HRH4 (0.80) | HRH4HRH1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL3233802 | 0.81 | TLR8 (0.71) | HRH4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL13329969 | 0.79 | HRH4 (0.57) | HRH4HRH1MEN1KMT2APTGDR | |
| SCHEMBL5170786 | 0.78 | HRH4 (0.49) | HRH4HRH1MEN1ALDH1A1KMT2A | |
| SCHEMBL3457749 | 0.77 | KMT2A (0.54) | HRH4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL3473227 | 0.74 | MEN1 (0.66) | HRH4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL416616 | 0.74 | MEN1 (0.66) | HRH4MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |