Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329888 | 1.00 | ALDH1A1 (0.46) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL15251346 | 0.88 | CPB1 (0.49) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL2826203 | 0.88 | CPB1 (0.49) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL16891978 | 0.86 | CPB1 (0.47) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL15251322 | 0.86 | CPB1 (0.47) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL5227905 | 0.85 | CPB1 (0.54) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL30401008 | 0.85 | CPB1 (0.54) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL30400185 | 0.85 | CPB1 (0.54) | ALDH1A1GAACPB1TSHRTACR1 | |
| SCHEMBL2823788 | 0.85 | CPB1 (0.54) | ALDH1A1GAACPB1TSHRTACR1 | |
| Hydrochloric Acid SCHEMBL2823828 | 0.84 | CPB1 (0.53) | ALDH1A1GAACPB1TSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010067125-A1 | 2- (PIPERIDIN-1-YL) -4-AZOLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | WO | disclosed |