Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356328 | 0.90 | ALDH1A1 (0.34) | ALDH1A1PROKR1FPR2 | |
| SCHEMBL3352647 | 0.90 | ALDH1A1 (0.34) | ALDH1A1PROKR1FPR2MGLLPIK3CA | |
| SCHEMBL13330897 | 0.89 | ALDH1A1 (0.32) | ALDH1A1PROKR1FPR2 | |
| SCHEMBL3356345 | 0.88 | ALDH1A1 (0.37) | ALDH1A1PROKR1FPR2 | |
| SCHEMBL3359564 | 0.80 | ALDH1A1 (0.32) | ALDH1A1PROKR1FPR2MGLL | |
| SCHEMBL3353165 | 0.79 | ALDH1A1 (0.35) | ALDH1A1PROKR1FPR2JAK2JAK1 | |
| SCHEMBL3354404 | 0.79 | ALDH1A1 (0.33) | ALDH1A1PROKR1FPR2 | |
| SCHEMBL3353857 | 0.77 | ALDH1A1 (0.36) | ALDH1A1PROKR1FPR2 | |
| SCHEMBL13308355 | 0.76 | MC4R (0.36) | ALDH1A1JAK2JAK1 | |
| SCHEMBL3358681 | 0.76 | LMNA (0.35) | ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |