Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354757 | 0.89 | ALDH1A1 (0.34) | CYP19A1NAMPTLSSKMT2AMCHR1 | |
| SCHEMBL13331642 | 0.88 | PSEN1 (0.36) | AKT2 | |
| SCHEMBL13331447 | 0.87 | AKT2 (0.34) | AKT2TARDBP | |
| SCHEMBL13330711 | 0.87 | PREP (0.34) | AKT2TARDBP | |
| SCHEMBL13330873 | 0.81 | NTRK1 (0.34) | NAMPT | |
| SCHEMBL3355489 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL3355879 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL13330872 | 0.78 | PREP (0.33) | NAMPTAKT2 | |
| SCHEMBL3352607 | 0.77 | PSEN1 (0.36) | — | |
| SCHEMBL13308393 | 0.77 | CHRM1 (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |