Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331447 | 0.98 | AKT2 (0.34) | PREPAKT2GAAPOLBRAB9A | |
| SCHEMBL3354647 | 0.88 | ALDH1A1 (0.36) | PREPGAAPOLBRAB9ANPC1 | |
| SCHEMBL13330902 | 0.87 | CYP19A1 (0.33) | AKT2TARDBP | |
| SCHEMBL3353086 | 0.86 | ALDH1A1 (0.36) | PREPGAAPOLBRAB9AL3MBTL1 | |
| SCHEMBL13331642 | 0.85 | PSEN1 (0.36) | AKT2L3MBTL1 | |
| SCHEMBL3354290 | 0.82 | NPC1 (0.37) | GAAPOLBRAB9ANPC1CASP1 | |
| SCHEMBL13330872 | 0.80 | PREP (0.33) | PREPAKT2 | |
| SCHEMBL13330957 | 0.79 | RAB9A (0.34) | PREPRAB9A | |
| SCHEMBL3353515 | 0.78 | ALDH1A1 (0.38) | PREPPOLBL3MBTL1 | |
| SCHEMBL3355879 | 0.78 | ALDH1A1 (0.36) | GAAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |