Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149521 | 1.00 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL8850268 | 1.00 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL10940220 | 0.92 | CYP4F2 (0.46) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL15255236 | 0.86 | MEN1 (0.41) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL8998689 | 0.86 | MEN1 (0.41) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL13547601 | 0.84 | CYP4F2 (0.44) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL28952305 | 0.83 | CES2 (0.40) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL11087126 | 0.83 | MAPT (0.44) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL28534829 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL25189076 | 0.81 | MEN1 (0.57) | MEN1KMT2AMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120901-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | FASGEN,INC (US) | 2010-05-13 | — | — | US | disclosed |
| US-7649012-B2 | Compounds, pharmaceutical compositions containing same, and methods of use for same | FASGEN, INC. (US) | 2010-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120901-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | CPT1A, CPT1B, CPT2 | MEN1 2374/4885KMT2A 4379/4885MAPT 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.