Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 7/20 | 0.38 |
| ▸ | CES1 | P23141 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910797 | 0.90 | FAAH (0.47) | MAPTMEN1KMT2AATMTP53 | |
| SCHEMBL28952305 | 0.85 | CES2 (0.40) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL12149521 | 0.83 | MEN1 (0.54) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL8850268 | 0.83 | MEN1 (0.54) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL13332175 | 0.83 | MEN1 (0.54) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL18612495 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL28723450 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL28978239 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL14445397 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL28070477 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |