Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765544 | 0.85 | CA1 (0.44) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL15947338 | 0.84 | CA1 (0.49) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL256594 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL148100 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL148099 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL17957327 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL875372 | 0.82 | CA1 (0.47) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL2411603 | 0.82 | CA1 (0.47) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL2171444 | 0.82 | CA1 (0.47) | CA1CA2CA7KMT2ACTSK | |
| Hydrochloric Acid SCHEMBL30428440 | 0.82 | CA1 (0.50) | CA1CA2CA7KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117295-B | Adefovir monothiol-amino acid ester mono-cholate derivative and preparation method thereof | 贵州医科大学 | 2020-05-22 | — | — | CN | disclosed |
| US-20110282081-A1 | Methods of Preparing 1-Deoxy-Sphingoid Bases and Derivatives Thereof | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| WO-2010085547-A2 | METHODS OF PREPARING 1-DEOXY-SPHINGOID BASES AND DERIVATIVES THEREOF | EMORY UNIVERSITY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-3997584-A | Substituted glycines and intermediates thereof | SMITHKLINE CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3994954-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282081-A1 | Methods of Preparing 1-Deoxy-Sphingoid Bases and Derivatives Thereof | DEGS1, SPHK1, SPHK2 | CA1 1708/4885CA2 3287/4885CA7 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.