Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 10/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333292 | 0.85 | CA1 (0.49) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL7765532 | 0.82 | CA1 (0.46) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL13618660 | 0.80 | CA1 (0.50) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL15081362 | 0.80 | CA1 (0.50) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL13050322 | 0.80 | CA1 (0.50) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL15947338 | 0.78 | CA1 (0.49) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL148100 | 0.77 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL148099 | 0.77 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL256594 | 0.77 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL17957327 | 0.77 | CA1 (0.52) | CA1CA2CA7KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104304-A1 | MULTIVALENT AVB3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009143-A1 | MULTIVALENT AVB3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 2000-02-24 | — | — | WO | disclosed |