Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657158 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38656730 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38655757 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38655867 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38657147 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21246240 | 0.85 | MAOA (0.40) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17382647 | 0.85 | CSNK1E (0.41) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38657408 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10307812 | 0.84 | CSNK1E (0.39) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38657422 | 0.84 | CYP2C19 (0.39) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062381-A1 | ORGANELLE-SPECIFIC DRUG DELIVERY | SHORR ROBERT (US) | 2010-06-03 | — | — | WO | disclosed |