Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307812 | 0.98 | CSNK1E (0.39) | CSNK1ECYP2C19CNR2CYP1A2CYP3A4 | |
| SCHEMBL38656325 | 0.88 | CYP2C19 (0.34) | CSNK1ECYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL38655757 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38655867 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38657147 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13333135 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38657158 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38656730 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21246240 | 0.85 | MAOA (0.40) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL38657408 | 0.85 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188726-B1 | PHARMACEUTICAL COMPOUNDS | RAFAEL PHARMACEUTICALS INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190119309-A1 | PHARMACEUTICAL COMPOUNDS | RAFAEL PHARMACEUTICALS, INC. | 2019-04-25 | — | — | US | disclosed |
| US-10179796-B2 | Pharmaceutical compounds | RAFAEL PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20170217998-A1 | PHARMACEUTICAL COMPOUNDS | RAFAEL PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
| US-20170217998-A1 | PHARMACEUTICAL COMPOUNDS | RAFAEL PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
| WO-2015195071-A1 | PHARMACEUTICAL COMPOUNDS | SHORR ROBERT (US) | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217998-A1 | PHARMACEUTICAL COMPOUNDS | SLC27A1, LIPA, ALOX12 | CSNK1E 4838/4885CYP2C19 1175/4885CNR2 742/4885 |
| US-10179796-B2 | Pharmaceutical compounds | SLC27A1, LIPA, ALOX12 | CSNK1E 4838/4885CYP2C19 1175/4885CNR2 742/4885 |
| US-20190119309-A1 | PHARMACEUTICAL COMPOUNDS | SLC27A1, LIPA, ALOX12 | CSNK1E 4838/4885CYP2C19 1175/4885CNR2 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.