Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664701 | 0.84 | PTPN1 (0.66) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL27705620 | 0.82 | SLC9A1 (0.69) | SLC9A1 | |
| SCHEMBL6915287 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL6913222 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL6914945 | 0.82 | HIPK2 (0.50) | PARP1PTPN1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL6916900 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL6916903 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL6914903 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL6914950 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL6915348 | 0.82 | PTPN1 (0.64) | PTPN1CYP1A2CYP2A6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100119510-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119510-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | F12, F2, CPB1 | PARP1 626/4885PTPN1 1868/4885LCK 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.