Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12351064 | 0.80 | — | — | |
| SCHEMBL14327682 | 0.78 | TRPA1 (0.31) | — | |
| SCHEMBL13839056 | 0.78 | CA1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL14041977 | 0.75 | — | — | |
| SCHEMBL12979886 | 0.75 | — | — | |
| SCHEMBL18499943 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHR | |
| SCHEMBL18808290 | 0.74 | — | — | |
| SCHEMBL16704709 | 0.74 | DRD1 (0.34) | — | |
| SCHEMBL19139884 | 0.72 | NR5A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5437291 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |
| US-7335659-B2 | Substituted 10-aryl-11H-benzo[b]fluorenes and 7-aryl-5, 6-dihydro-benzo[a]anthracenes for selective effects on estrogen receptors | N.V. ORGANON (NL) | 2008-02-26 | — | — | US | disclosed |
| US-7335659-B2 | Substituted 10-aryl-11H-benzo[b]fluorenes and 7-aryl-5, 6-dihydro-benzo[a]anthracenes for selective effects on estrogen receptors | N.V. ORGANON (NL) | 2008-02-26 | — | — | US | disclosed |