Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442538 | 0.97 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13849512 | 0.97 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL42203 | 0.97 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7092944 | 0.97 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL255602 | 0.97 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL9842020 | 0.94 | TSHR (0.48) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| Water SCHEMBL28115835 | 0.94 | TSHR (0.48) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18857848 | 0.89 | TSHR (0.43) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28297278 | 0.89 | TSHR (0.43) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8458943 | 0.85 | TSHR (0.40) | TSHRTP53SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971335-A | Reversibly terminating primer extension reagents | BENNER STEVEN ALBERT | 2013-03-13 | — | — | CN | disclosed |
| US-8212020-B2 | Reagents for reversibly terminating primer extension | BENNER STEVEN ALBERT (US) | 2012-07-03 | — | — | US | disclosed |
| US-20110275124-A1 | Reagents for reversibly terminating primer extension | BENNER STEVEN A | 2011-11-10 | — | — | US | disclosed |
| WO-2010110775-A1 | REAGENTS FOR REVERSIBLY TERMINATING PRIMER EXTENSION | BENNER STEVEN ALBERT (US) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275124-A1 | Reagents for reversibly terminating primer extension | RNGTT, POLRMT, DNTT | TSHR 672/4885TP53 764/4885SLC1A3 4475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.