SCHEMBL133366

SCHEMBL133366

CCOC(=O)c1cccc(N)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
MAOA P21397 1/20 0.62
ELANE P08246 1/20 0.56
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
ADRB2 P07550 2/20 0.56
ADRB1 P08588 2/20 0.56
ADRB3 P13945 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CDC25B P30305 2/20 0.53
CHRNB2 P17787 1/20 0.53
CHRNA4 P43681 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29465556 1.00 LMNA (0.62) LMNACYP1A2CYP3A4MAOAELANE
Methane SCHEMBL15286491 0.98 LMNA (0.61) LMNACYP1A2CYP3A4MAOAELANE
Hydrochloric Acid SCHEMBL642777 0.98 LMNA (0.61) LMNACYP1A2CYP3A4MAOAELANE
Ethylamine SCHEMBL27494386 0.95 LMNA (0.57) LMNACYP1A2CYP3A4MAOAELANE
3-Aminobenzoic Acid SCHEMBL8220213 0.94 LMNA (0.56) LMNACYP1A2CYP3A4MAOAELANE
SCHEMBL983965 0.92 LMNA (0.54) LMNACYP1A2CYP3A4MAOAELANE
SCHEMBL285618 0.92 LMNA (0.54) LMNACYP1A2CYP3A4MAOAELANE
SCHEMBL29370485 0.92 LMNA (0.54) LMNACYP1A2CYP3A4MAOAELANE
Hydrochloric Acid SCHEMBL7319745 0.91 ELANE (0.53) LMNACYP1A2CYP3A4MAOAELANE
Methane SCHEMBL2132580 0.91 ELANE (0.53) LMNACYP1A2CYP3A4MAOAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2811 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119243362-A Long-acting antibacterial fiber and preparation method thereof 江苏恒科新材料有限公司 2025-01-03 CN claimed
CN-115466341-B Ashless dispersant and preparation method thereof 新乡市瑞丰新材料股份有限公司 2024-12-20 CN claimed
CN-118908864-A WNT signal transduction inhibitor 福建医科大学附属口腔医院 2024-11-08 CN claimed
CN-118546481-B Insulating sheath for electric wire and cable 华旗线缆有限公司 2024-09-27 CN claimed
CN-118621394-A Pulse copper electroplating solution applied to circuit board 南雄市溢诚化工有限公司 2024-09-10 CN claimed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO claimed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US claimed
CN-118546481-A Insulating sheath for electric wire and cable 华旗线缆有限公司 2024-08-27 CN claimed
CN-118443813-A Method for measuring benzocaine related substances 李宏 2024-08-06 CN claimed
CN-115466341-A Ashless dispersant and preparation method thereof 新乡市瑞丰新材料股份有限公司 2022-12-13 CN claimed
US-20030083331-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2003-05-01 US claimed
US-20030032644-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2003-02-13 US claimed
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
US-5391699-A Containing an aromatic amine carboxylate, heat resistance BRIDGESTONE CORPORATION (JP) 1995-02-21 US claimed
EP-0571095-A2 Polyester copolymer and process for the production of the same BRIDGESTONE CORPORATION (JP) 1993-11-24 EP claimed
US-4970297-A CONTAINING ISOXAZOLE RING SYNTEX (U.S.A.) INC. (US) 1990-11-13 US claimed
EP-0022281-A1 Amino compounds and use of amino compounds as antioxydant in lubricating oils UNIROYAL, INC. (US) 1981-01-14 EP claimed