SCHEMBL133367

SCHEMBL133367

O=C(OCCOCCOC(=O)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.69
TSHR P16473 2/20 0.69
ALDH1A1 P00352 2/20 0.69
CHRM1 P11229 1/20 0.69
SLC6A2 P23975 1/20 0.69
KDR P35968 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
ESR2 Q92731 3/20 0.66
LMNA P02545 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
MAPK1 P28482 2/20 0.65
CYP2D6 P10635 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C19 P33261 1/20 0.65
NR1H2 P55055 1/20 0.65
RNASEL Q05823 1/20 0.65
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132495 1.00 ESR1 (0.69) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL132567 0.94 ESR1 (0.77) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL9001430 0.91 ESR1 (0.64) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL7552086 0.88 ESR1 (0.81) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL7545735 0.88 ESR1 (0.81) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL19763408 0.88 ESR1 (0.69) ESR1TSHRALDH1A1CHRM1SLC6A2
Ethylene Glycol SCHEMBL9464604 0.88 ESR1 (0.69) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL7548561 0.87 ESR1 (0.73) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL10935381 0.87 ESR1 (0.54) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL17034380 0.87 TSHR (0.59) ESR1TSHRALDH1A1CHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714845-B1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENT SCIMED INC (US) 2015-07-22 EP claimed
US-8497342-B2 Liquid crystal block copolymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US claimed
US-20120309901-A1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-12-06 US claimed
WO-2012166260-A1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-12-06 WO claimed
US-6486293-B1 Electrophotographic photoconductor and method of producing aromatic polycarbonate resin for use in the photoconductor RICOH COMPANY, LTD. (JP) 2002-11-26 US claimed
EP-2714845-B1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENT SCIMED INC (US) 2015-07-22 EP disclosed
EP-2714845-A1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME Boston Scientific Scimed, Inc. (US) 2014-04-09 EP disclosed
US-8497342-B2 Liquid crystal block copolymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
US-8497342-B2 Liquid crystal block copolymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
US-8497342-B2 Liquid crystal block copolymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
US-8497342-B2 Liquid crystal block copolymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
WO-2012166260-A1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-12-06 WO disclosed
US-5976746-A ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER RICOH COMPANY, LTD. (JP) 1999-11-02 US disclosed
US-5942363-A POLYCARBONATE RESIN HAVING TRIARYLAMINE STRUCTURE IN MAIN CHAIN; CHARGE TRANSFER AGENTS RICOH COMPANY, LTD. (JP) 1999-08-24 US disclosed
US-5871876-A CHARGE TRANSPORT MATERIAL WITH POLYCARBONATE STRUCTURE HAVING TRIARYLAMINO GROUPS; PHTHALOCYANINE CHARGE GENERATING COMPOUND; WEAR RESISTANCE; COPIERS RICOH COMPANY, LTD. (JP) 1999-02-16 US disclosed
US-5853935-A Electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 1998-12-29 US disclosed
US-5846680-A Electrophotographic photoconductor and aromatic polycarbonate resin for use therein RICOH COMPANY, LTD. (JP) 1998-12-08 US disclosed
US-5840454-A Aromatic polycarbonate and electrophotographic photosensitive medium using same RICOH COMPANY, LTD. (JP) 1998-11-24 US disclosed
US-5789128-A Electrophotographic photoconductor and aromatic polycarbonate resin for use therein RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed
US-5723243-A MULTILAYER ELECTROCONDUCTOR SUPPORTS WITH AROMATIC POLYCARBONATES RICOH COMPANY, LTD. (JP) 1998-03-03 US disclosed