SCHEMBL132567

SCHEMBL132567

O=C(OCCOC(=O)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.77
TSHR P16473 2/20 0.77
ALDH1A1 P00352 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
CHRM1 P11229 1/20 0.77
SLC6A2 P23975 1/20 0.77
KDR P35968 1/20 0.77
ESR2 Q92731 2/20 0.72
LMNA P02545 3/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
MAPK1 P28482 2/20 0.71
CYP2D6 P10635 2/20 0.71
CYP1A2 P05177 1/20 0.71
CYP2C19 P33261 1/20 0.71
NR1H2 P55055 1/20 0.71
RNASEL Q05823 1/20 0.71
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
CA12 O43570 2/20 0.69
CA1 P00915 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133367 0.94 ESR1 (0.69) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL19763408 0.94 ESR1 (0.69) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL132495 0.94 ESR1 (0.69) ESR1TSHRALDH1A1TDP1CHRM1
Ethylene Glycol SCHEMBL9464604 0.94 ESR1 (0.69) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL5152874 0.92 ESR1 (0.80) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL8638181 0.91 ESR1 (0.79) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL2880231 0.91 ESR1 (0.79) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL756904 0.90 ESR1 (0.70) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL19046865 0.90 ESR1 (0.83) ESR1TSHRALDH1A1TDP1CHRM1
SCHEMBL2488148 0.89 ESR1 (0.69) ESR1TSHRALDH1A1TDP1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6486293-B1 Electrophotographic photoconductor and method of producing aromatic polycarbonate resin for use in the photoconductor RICOH COMPANY, LTD. (JP) 2002-11-26 US claimed
CN-111918895-B Cosmetic raw material using core-shell polymer particles and oil-in-water emulsion cosmetic 株式会社资生堂 2023-07-14 CN disclosed
US-11649203-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-05-16 US disclosed
US-20210171883-A1 ANTIVIRAL WIPER FUJIFILM CORPORATION (JP) 2021-06-10 US disclosed
EP-3237487-B1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS UNIV RUTGERS (US) 2021-02-17 EP disclosed
US-20200369597-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-11-26 US disclosed
US-10774030-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-09-15 US disclosed
US-10725391-B2 Electrophotographic photoreceptor and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2020-07-28 US disclosed
US-10266647-B2 Biocompatible iodinated diphenol monomers and polymers RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-04-23 US disclosed
US-10266647-B2 Biocompatible iodinated diphenol monomers and polymers RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-04-23 US disclosed
EP-0095189-B1 IMPROVED POLYESTER BLOCK COPOLYMER COMPOSITION Toyo Boseki Kabushiki Kaisha (JP) 1987-03-04 EP disclosed
EP-0203604-A2 Polyester film for magnetic recording media TEIJIN LIMITED (JP) 1986-12-03 EP disclosed
US-4584353-A POLYBUTYLENE YEREPHTHLATE, LACTONE, EPOXY COMPONENTS TOYO BOSEKI KABUSHIKI KAISHA (JP) 1986-04-22 US disclosed
EP-0089643-B1 IMPROVED POLYESTER TYPE BLOCK COPOLYMER COMPOSITION Toyo Boseki Kabushiki Kaisha (JP) 1985-12-27 EP disclosed
EP-0148787-A2 Positive type photosensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-07-17 EP disclosed
US-4500686-A CRYSTALLINE AROMATIC POLYESTERLACTONE COPOLYMER MELT-ADMIXED WITH EPOXY COMPOUND TOYO BOSEKI KABUSHIKI KAISHA (JP) 1985-02-19 US disclosed
EP-0095189-A2 Improved polyester block copolymer composition Toyo Boseki Kabushiki Kaisha (JP) 1983-11-30 EP disclosed
EP-0089643-A2 Improved polyester type block copolymer composition Toyo Boseki Kabushiki Kaisha (JP) 1983-09-28 EP disclosed
US-4178283-A BIS/HYDROXYBENZOATES/ OR POLYPHENYL PHOSPHONATES RHONE-POULENC-TEXTILE (FR) 1979-12-11 US disclosed
US-4117042-A FLAMEPROOFING POLYESTERS RHONE-POULENC-TEXTILE (FR) 1978-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10266647-B2 Biocompatible iodinated diphenol monomers and polymers PTGDR, DDT, HPGDS ESR1 483/4885TSHR 1006/4885ALDH1A1 2768/4885
US-20210171883-A1 ANTIVIRAL WIPER CGAS, PRKX, PDE4C ESR1 4000/4885TSHR 4670/4885ALDH1A1 1983/4885
US-10774030-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, HPD ESR1 1565/4885TSHR 4168/4885ALDH1A1 920/4885
US-20200369597-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, TYRO3 ESR1 1387/4885TSHR 3991/4885ALDH1A1 1461/4885
US-11649203-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, TYRO3 ESR1 1387/4885TSHR 3991/4885ALDH1A1 1461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.