Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13337066 | 0.90 | DPP4 (0.36) | DPP4DPP8DPP7 | |
| SCHEMBL13337075 | 0.88 | DPP4 (0.35) | DPP4DPP8DPP7 | |
| SCHEMBL13337032 | 0.85 | DPP4 (0.43) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL19036871 | 0.84 | DPP4 (0.50) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL13580025 | 0.84 | DPP4 (0.50) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL23056586 | 0.84 | DPP4 (0.50) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL13522030 | 0.84 | DPP4 (0.50) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL13337063 | 0.84 | DPP4 (0.50) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL13337058 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL13337059 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130581-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN | THE UNIVERSITY OF QUEENSLAND | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130581-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN | OPRL1, CRH, OPRK1 | DPP4 300/4885DPP8 325/4885DPP7 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.