SCHEMBL13337084

SCHEMBL13337084

CCC/C=C(/C=C/C=O)CC

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.39
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.33
GAPDH P04406 2/20 0.31
DDAH1 O94760 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13825214 1.00 TRPA1 (0.39) TRPA1ALDH1A1TSHRGAPDHDDAH1
SCHEMBL24784446 0.78
SCHEMBL12213502 0.77 TRPA1 (0.33) TRPA1
SCHEMBL366896 0.77
SCHEMBL366897 0.77
SCHEMBL9122134 0.77
SCHEMBL9122142 0.77
SCHEMBL6554564 0.77
SCHEMBL29068787 0.76 TRPA1 (0.41) TRPA1ALDH1A1TSHRGAPDHDDAH1
SCHEMBL14847483 0.75 ALDH1A1 (0.38) TRPA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871982-B2 Hydrogenation of dienals with rhodium complexes under carbon monoxide free atmosphere FIRMENICH SA (CH) 2014-10-28 US disclosed
EP-2196454-A2 Exo-and diastereo-selective syntheses of himbacine analogs SCHERING CORPORATION (US) 2010-06-16 EP disclosed