Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977447 | 0.94 | CHRM3 (0.33) | HTTCHRM3 | |
| SCHEMBL4373179 | 0.86 | HTT (0.38) | CYP1A2HTTCHRM3 | |
| SCHEMBL4366182 | 0.84 | CYP1A2 (0.37) | CYP1A2HTTCHRM3 | |
| SCHEMBL25453177 | 0.82 | PSEN1 (0.38) | CYP1A2CHRM3 | |
| SCHEMBL18965497 | 0.82 | PSEN1 (0.38) | CYP1A2CHRM3 | |
| SCHEMBL13910201 | 0.82 | PSEN1 (0.38) | CYP1A2CHRM3 | |
| SCHEMBL22473381 | 0.81 | PKM (0.41) | CYP1A2CHRM3 | |
| SCHEMBL22388304 | 0.81 | CYP1A2 (0.35) | CYP1A2CHRM3 | |
| SCHEMBL3124831 | 0.81 | CYP1A2 (0.35) | CYP1A2CHRM3 | |
| SCHEMBL4371060 | 0.81 | CYP1A2 (0.35) | CYP1A2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130469-A1 | 2, 6-NAPHTHRIDINE DERIVATIVES | VAN EIS MAURICE | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130469-A1 | 2, 6-NAPHTHRIDINE DERIVATIVES | PKN1, PKN2, CDK9 | CYP1A2 3548/4885HTT 3898/4885CHRM3 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.