Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334076 | 0.82 | MAPT (0.48) | MAPTL3MBTL1SLC1A2KMT2AMEN1 | |
| SCHEMBL1332949 | 0.82 | MAPT (0.41) | F10MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL28331905 | 0.77 | MAPT (0.40) | MAPTL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL3700126 | 0.70 | MAPT (0.40) | F10MAPTL3MBTL1KMT2ANPC1 | |
| SCHEMBL28356124 | 0.69 | MAPT (0.44) | F10MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL7119512 | 0.68 | KDM1A (0.39) | KMT2AMEN1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL1331851 | 0.68 | MAPT (0.44) | F10MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL4671491 | 0.68 | CNR1 (0.35) | MAPTL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL4670884 | 0.67 | KDM1A (0.35) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL7473370 | 0.67 | MAPT (0.41) | MAPTL3MBTL1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3367143-B1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL INC (US) | 2023-01-11 | — | — | EP | claimed |
| EP-1639058-B1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2020-10-21 | — | — | EP | claimed |
| EP-3367143-A1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | Transitions Optical, Inc. (US) | 2018-08-29 | — | — | EP | claimed |
| US-7847998-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2010-12-07 | — | — | US | claimed |
| US-7505189-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2009-03-17 | — | — | US | claimed |
| US-20070098968-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-05-03 | — | — | US | claimed |
| US-20070075388-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-04-05 | — | — | US | claimed |
| EP-1642160-A1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2006-04-05 | — | — | EP | claimed |
| EP-1639058-A1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-29 | — | — | EP | claimed |
| WO-2005005570-A1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005006035-A1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| US-20050012998-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2005-01-20 | — | — | US | claimed |
| US-20050004361-A1 | Thermally reversible; absorption ratio greater than 2.3 | TRANSITIONS OPTICAL LIMITED (IE) | 2005-01-06 | — | — | US | claimed |
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-3367143-B1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL INC (US) | 2023-01-11 | — | — | EP | disclosed |
| WO-2005005570-A1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2005-01-20 | — | — | WO | disclosed |
| WO-2005006035-A1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2005-01-20 | — | — | WO | disclosed |
| US-20050012998-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2005-01-20 | — | — | US | disclosed |
| US-20050004361-A1 | Thermally reversible; absorption ratio greater than 2.3 | TRANSITIONS OPTICAL LIMITED (IE) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004361-A1 | Thermally reversible; absorption ratio greater than 2.3 | CCND1, CCND3, CCND2 | F10 520/4885MAPT 4150/4885L3MBTL1 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.