Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.38 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479031 | 0.90 | SMN1; SMN2 (0.43) | MAPTL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24620658 | 0.89 | KDM4E (0.40) | MAPTL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5615531 | 0.87 | ALDH1A1 (0.43) | MAPTKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5615321 | 0.85 | SMN1; SMN2 (0.43) | MAPTL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3823227 | 0.85 | SMN1; SMN2 (0.39) | MAPTL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3041820 | 0.84 | TP53 (0.38) | MAPTL3MBTL1TP53THRBKMT2A | |
| SCHEMBL24620639 | 0.84 | SMN1; SMN2 (0.42) | MAPTL3MBTL1TP53KMT2AALDH1A1 | |
| SCHEMBL24620629 | 0.83 | SMN1; SMN2 (0.42) | MAPTL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8721095 | 0.83 | KMT2A (0.40) | MAPTKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3829545 | 0.83 | SMN1; SMN2 (0.37) | MAPTL3MBTL1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | claimed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | claimed |